Development of Individual Insulin Infusion Profiles for Open Loop Infusion Systems
نویسندگان
چکیده
منابع مشابه
Development of individual insulin infusion profiles for open loop infusion systems.
A computer controlled syringe-type insulin infusion pump storing up to 254 different infusion rates, eight different meal programs and two different basal rates automatically changeable during 24 h in EPROM was used for insulin infusion applying a wavy step profile. This profile approaching the physiological postprandial insulin secretion of the B-cell was calculated by an algorithm following t...
متن کاملDevelopmental and application of insulin infusion profiles for therapy of type-I diabetics with portable insulin infusion systems.
We studied the insulin requirements of seven insulin-dependent diabetics applying a glucose controlled insulin infusion system. The data were transformed into individually programmed and rectangular profiles. The MAGE, a measure of blood sugar fluctuations, was significantly lower when individually programmed step profiles were used (P less than 0.005) than it was when rectangular profiles were...
متن کاملChanges in Basal Insulin Infusion Rates With Subcutaneous Insulin Infusion
OBJECTIVE Evaluation of the time required until a change in the basal insulin infusion rate with an insulin pump induces subsequent changes in the metabolic effect. RESEARCH DESIGN AND METHODS In this euglycemic glucose clamp study, 10 male subjects with type 1 diabetes received three different subcutaneous insulin infusion rates (0.5, 1.0, and 2.0 units/h; for 4 h each) of insulin lispro (IL) ...
متن کاملProportional Insulin Infusion in Closed-Loop Control of Blood Glucose
A differential equation model is formulated that describes the dynamics of glucose concentration in blood circulation. The model accounts for the intake of food, expenditure of calories and the control of glucose levels by insulin and glucagon. These and other hormones affect the blood glucose level in various ways. In this study only main effects are taken into consideration. Moreover, by maki...
متن کاملA review of the security of insulin pump infusion systems.
Insulin therapy has enabled patients with diabetes to maintain blood glucose control to lead healthier lives. Today, rather than injecting insulin manually using syringes, a patient can use a device such as an insulin pump to deliver insulin programmatically. This allows for more granular insulin delivery while attaining blood glucose control. Insulin pump system features have increasingly bene...
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ژورنال
عنوان ژورنال: Hormone and Metabolic Research
سال: 1984
ISSN: 0018-5043,1439-4286
DOI: 10.1055/s-2007-1014733